Analysis Of Lung Cancer Incidence Relating To Air
Pollution Levels Adjusting For Cigarette Smoking:
A Case-control Study
Author(s)
P. R. Band, H. Jiang & J. M. Zielinski
Abstract
A case-control study (lung cancer: 2711; age and sex matched non-lung cancer
controls: 2711) encompassing the years 1986-2004 was undertaken further to the
results of increased mortality and cancer incidence in Windsor, Canada. The
objective was to investigate associations between lung cancer incidence and
exposure to air pollutants controlling for cigarette smoking and duration of
residence. A nominal file of cases and controls ascertained by the Ontario Cancer
Registry was obtained from Cancer Care Ontario; smoking information and
addresses of residence within Windsor were obtained respectively from medical
charts at the Windsor Regional Cancer Centre and from the Windsor City
Directories. For each case and control and for each air pollutant, a cumulative
exposure was calculated based on duration of residence at each address location;
the centroid of postal codes of addresses was used as proxy for residential
location. For each location, annual NO2 and SO2 levels were estimated, using
Land Use Regression based on results from 54 monitors within Windsor. Results
obtained from conditional likelihood regression for matched or stratified data,
(including sex, age at diagnosis, numbers of cigarette smoked per day and
duration of smoking as covariates) are presented.
Keywords: air pollution, cigarette smoking, lung cancer, case-control study.
Keywords
air pollution, cigarette smoking, lung cancer, case-control study
Related Book
Other papers in this volume
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