Numerical Modelling Of Liquid-liquid Flow Related To Countercurrent
Chromatography (CCC)
Author(s)
C.S. König & I.A. Sutherland
Abstract
Numerical modelling of liquid-liquid flow
related to countercurrent chromatography
(CCC)
C. S. Konig & I. A. Sutherland
Brunel Institute for Bioengineering, Brunel University, UK
Abstract
The CCC method is based on interface mass transfer between two immiscible
liquids that move countercurrently. To be able to predict interface mass transfer
for a CCC system accurately, the correct interface prediction is essential. In the
present work, our previous numerical and experimental studies of countercurrent
flow in inclined and oscillating tubes have been extended for different CCC
phase systems. Furthermore the numerical models have been extended to circular
and coiled tubes which are rotated centrally. The results indicate that mixing due
to secondary motions is significant during the initial stages. However, their
influence decreases as a quasi-steady state is approached in the cases studied.
1 Introduction
CCC is a form of liquid-liquid chromatography that allows to separate
components from com
Keywords
Related Book
Other papers in this volume
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