Modelling Nanoparticle Transport In An Animal
Exposure Chamber: A Comparison Between
Numerical And Experimental Measurements
Author(s)
F. Morency & S. Hallé
Abstract
Modelling nanoparticle transport in an animal
exposure chamber: a comparison between
numerical and experimental measurements
F. Morency & S. Hallé
Département de Génie Mécanique, École de Technologie Supérieure,
Canada
Nanoparticles transport in an exposure chamber is investigated using
computational fluid dynamics (CFD). This exposure chamber is used to assess
the lung toxicity in rats resulting from the inhalation of airborne NPs. The
mathematical model for airflow is based on the three-dimensional Reynoldsaveraged
Navier-Stokes equations with turbulence modelling. Simulations of
airborne NPs are based on assumptions such that their motions are similar to the
ones of a single sized diameter distribution of a passive contaminant.
Keywords: nanoparticles, CFD, exposure chamber, passive contaminant.
1 Introduction
The evaluation of the potential hazards for human health associated with
inhalation or other form of contact with nanoparticles (NPs) is a question of
much interest in the scientific community. Indeed, the phenomenal emergence of
various types of nanotechnologies led many governmental agencies to present
discussion papers on the safe use of nanometric scale particles, herein called
NPs. These international reports are unanimous in supporting proactive measures
to ensure the safety of workers exposed to NPs [1, 2].
One of the basic elements for the risk assessment evaluation in a work
environment consists in an adequate characterization of the degree of exposure.
In the case of exposition to airborne NPs, numerical simulations could be used
advantageously as a tool to safely predict these exposure levels. In order to
achieve this though, the development of models is still required. It is expected
that these models once validated will make it possible to predict the behaviour of
airborne NPs in a workplace environment, to evaluate the effective exposure of
Keywords
nanoparticles, CFD, exposure chamber, passive contaminant
Related Book
Other papers in this volume
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