Applications Of Shock Wave Research
To Medicine
Author(s)
K. Takayama & K. Ohtani
Abstract
Applications of shock wave research conducted in Tohoku University are briefly
described. Its is emphasized that underwater shock wave research and its
connection to bubble dynamics are one of the most important physical
backgrounds to interpret tissue damages occurring during shock wave therapy. In
addiction to ESWL, revascularization of cerebral thrombosis by using a laser
induced liquid jet and its application to the water jet dissection method are
presented. Lastly the development of a laser ablation induced drug delivery
system is briefly described. In these applications implicitly and explicitly shock
waves and their interaction with the bubble always play an important role.
Keywords: shock wave therapy, water jet, gene delivery.
1 Introduction
In the Shock Wave Research Center of the Institute of Fluid Science, Tohoku
University, the first underwater shock wave research was performed in 1975 in
conjunction with bubble dynamic studies. Based on these results, in 1982 we
initiated a collaboration with the School of Medicine, Tohoku University for
exploring extracorporeal shock wave lithotripsy (ESWL), which is a noninvasive
disintegration of kidney stones by means of underwater focusing onto
kidney stones from outside a human body (Kuwahara and Takayama [12]).
A prototype ESWL device was constructed in 1983 and eventually approved
in 1987 for clinical therapy by the Ministry of Health in Japan. The existing
device developed at the Dornier Systems employed electrical discharges for
shock generation (Chaussey et al [2]), however, in our device shock waves were
generated by exploding silver azide pellets. It was probably one of the most
unique uses of primary explosive for peaceful purpose (Glass [3]). Despite its
Keywords
shock wave therapy, water jet, gene delivery.
Related Book
Other papers in this volume
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