Cavitational Tissue Erosion By Therapeutic Ultrasound
Author(s)
Z. Xu, A. Ludomirsky, L. Y. Eun, T. L. Hall, B. C. Tran,
J. B. Fowlkes & C. A. Cain
Abstract
Cavitational tissue erosion by therapeutic
ultrasound
Z. XU', A. ~udomirsk~~, L.Y. ELK?, T.L. all', B.C. ran',
J. B. ~owlkes' & C.A. cainl
1 Department of Biomedical Engineering, University of Michigan, Ann
Arbor, USA
2 Division of Pediatric Cardiology, University of Michigan, Ann Arbor,
USA
Abstract
The ability of ultrasound to produce highly controlled tissue erosion through
cavitation was investigated in this paper. Studies were performed in vitro on
porcine atrial wall with a 788 kHz single element transducer. We show that the
tissue can be eroded away at a relatively constant etching rate. The relationship
between the etching rate and other parameters (i.e. pulse repetition frequency
(PRF), pulse duration (PD), and gas saturation) has been explored. The
relationship between (a) the etching rate and PRF and (b) the etching rate and PD
were investigated by setting PD to 3, 6, 12, 24 cycles in the waveform, varying
PRF for each PD and keeping the gas saturation constant at 40-55%. (c) The
Keywords
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