Relation Between Ambient Air And Breath
Volatile Organic Compounds
Author(s)
H. Dhondt, E. Goelen, G. Koppen & L. Verschaeve
Abstract
Breath analysis is a non-invasive tool that can be used to measure body impact
following exposure to air pollutants. A method for collecting and analyzing
exhaled breath was developed and used to compare individual exhaled breath
volatile organic compounds (VOCs) with ambient air VOCs. Exhaled breath was
collected in Teflon bags and analyzed using thermal desorption gas
chromatography – mass spectrometry. The repeatability of this method was
examined following analysis of 10 breath samples of each of three subjects. An
environmental health study including 56 3-year-old children in Flanders
examined abundances of VOCs in exhaled breath in relation to the presence of
these VOCs in ambient air. It was demonstrated that a number of VOCs were
either significantly retained or cleared by the body.
Keywords: exhaled breath, volatile organic compounds, ambient air.
1 Introduction
Monitoring the influence of environmental pollution on human health has
increased remarkably during the past decades. So far, methods to evaluate
exposure to or impact of these environmental pollutants mainly involved the
collection and analysis of biological media such as blood or urine. Measuring
biomarkers in breath, however, is a very attractive approach to monitoring
environmental impact because it is non-invasive and makes repeated sampling
possible [1]. Breath contains valuable information because the pulmonary
alveolar membrane consists of a thin barrier separating the air in the alveoli of
the lung from the blood in the capillaries.
Keywords
exhaled breath, volatile organic compounds, ambient air.
Related Book
Other papers in this volume
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