Calculation Of Stress And The Absorption Of
Angiotensin In The Left Ventricle Based On
Two Dimensional Echocardiograms And MRIs
Author(s)
A. K. Macpherson, S. Neti, M. Averbach & P. A. Macpherson
Abstract
A cardiologist could make a more accurate diagnosis if the data on the stress and
absorption of Angiotensin II in the patient were more readily available. Currently
one of the most widely used diagnostic tools is the two dimensional
echocardiogram which can generate information to predict levels of stress. An
MRI of the heart provides full volumetric coverage of the heart and is more
accurate than echocardiograms in calculating left ventricular function. For
example in one instance the calculation of the ejection fraction based on
echocardiograms was measured to be 65 percent but use of MRI resulted in 79
percent ejection. The calculation of stress must be accomplished quickly so that
the information can be integrated with other clinical information to assist with
decision making. Presently this requires that the MRI results be limited to two
dimensions. The present study compares the boundary conditions for stress
calculations obtained from echocardiograms with those using two dimensional
MRI data. An obstacle is that the two dimensional slice shown by an
echocardiogram is difficult to relate to a slice of an MRI. It is shown that errors
in using echocardiograms can be significant at the end of systole when
myocardial stresses may be maximal. This is particularly true around the apex
where the stress is often considerable. Using the MRI data, results of stress
calculations are presented as well as the conditions for the absorption of Ang II.
The results are significantly different from those calculated using
echocardiograms.
Keywords: left ventricle, echocardiograms, MRI, ventricular stress, clinical
diagnosis, blood flow.
Keywords
left ventricle, echocardiograms, MRI, ventricular stress, clinical
diagnosis, blood flow.
Related Book
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