Advanced Cardiovascular Physiology Studied By Applying The
Equivalent Electronic Circuit
Author(s)
M. Jelenc, T. Podnar, F. Runovc & M. Kordaš
Abstract
Advanced cardiovascular physiology studied
by applying the equivalent electronic circuit
M. ~elenc', T. ~odnar', F. RU~OVC' and M. ~ o r d a ~ ~
i University Hospital of'Puedia~ric.r, Ljubljana, Slovenia
' ~ a c u l t ~ of Natural Science and Engineering, Ljubljana, Slovenia
3 Institute qf Pathophysiology, Ljubljana, Sloveniu
Abstract
The equivalent electronic circuit, developed to simulate cardiovascular
physiology, is upgraded to incorporate negative feed-back loops. In this way
homeostasis of the arterial pressure is simulated in left ventricular failure both if
the feed-back loops are disconnected from, or connected to, their target organs.
The results show that in left ventricular failure homeostasis strongly supports the
cardiovascular system both by modulating Starling mechanism(s) of the heart
and by modulating the tone of the venous system.
1 Introduction
There are various approaches in modelling methodology for physiology and
medicine (reviewed in [l]). However, recently it has been
Keywords
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