A Geometric Model Analysis Of Conductive Airways In
Expiratory Flow Limitation During Artificial Ventilation
Author(s)
G. Cevenini, F. Bernardi, M. R. Massai & P. Barbini
Abstract
A geometric model analysis of conductive
airways in expiratory flow limitation during
artificial ventilation
G. Cevenini, F. Bernardi, M.R. Massai, P. Barbini
Department of Surgevy and Bioengineering, Siena University, Siena, Italy
Abstract
Expiratory flow limitation (EFL) was simulated in mechanical ventilation
through a recently proposed tracheobronchial tree model which reproduces
breathing mechanics in the time-domain using Weibel's symmetrical description
of lung anatomy considered as 17 upper generations conducting air and seven
deeper generations where gas exchange takes place. The model allows for flow
turbulence, inertance and tissue viscoelasticity to be represented nonlinearly and
distributed along the tracheobronchial tree in a lumped parameter description. An
electric analogue of the simulator, consisting of a RLC ladder network, was
numerically implemented by Matlab-Simulink software. Normal conditions and
chronic obstructive pulmonary disease (COPD) were simulated by setting mode
Keywords
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