Fundamentals Of Alveolar Diffusion: Impact Of Microscopic Solid Particles
Author(s)
V.Kulish
Abstract
Fundamentals of alveolar diffusion: impact of
microscopic solid particles
V. Kulish
School of Mechanical and Production Engineering,
Nanyang Technological University, Singapore
Abstract
It is demonstrated that diffusion becomes the dominating factor in lower branches
of the respiratory duct of humans. A novel mathematical model, based on
transport through porous media, for simulating numerically the spatial and
temporal gas diffusion process within the alveolar region of the lung is discussed.
The model depends on a representative physical property of the alveolar region
termed effective diffisivity, function of the diffusivity, solubility, morphology and
interface topography of each alveolar constituent. Unfortunately, the direct
determination of the effective diffusivity of the alveolar region is impractical
because of the difficulty in describing the internal geometry of each alveolar
constituent. However, the transient solution of the macroscopic model can be
used in conjunction with the l
Keywords
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