Index For Cardiac Dysfunction Of Left-ventricular Filling Phase
Author(s)
L. Zhong, D.N. Ghista & E.Y-K. Ng
Abstract
Index for cardiac dysfunction of leftventricular
filling phase
L. Zhong, D.N. Gliista & E.Y-K. Ng
College of Engineering, ~Cchool of Mechanical and Production
Engineering, Nanyang Technological University, Singapore
Abstract
Left ventricular (LV) diastolic dysfunction often precedes systolic dysfimction.
Hence, the assessment of LV diastolic function is imperative for the early
diagnosis of the disease, and this phase of the cardiac cycle has not been
adequately analyzed. Thus, this study aims to develop a model of LV diastolic
performance, in terms of LV compliance, resistance-to-filling and inertia, which
are the indices of LV-pump's filling performance or behavior. Therefrom, we
have developed a novel filling-phase index (FLI) as well as the diastolic
pressure-time profile and provided the basis of their noninvasive determination.
By evaluating the range of FLI, it is possible to differentially diagnose diastolic
dysfunction.
1 Introduction
The human LV is the chamber of the heart that is
Keywords
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