Effect Of Specimen Size On Cancellous Bone
Microstructural Parameters
Author(s)
K. Tanaka, S. Sezaki, S. Enoki & T. Katayama
Abstract
As the average life span of Japanese people continues to extend, the increasing
incidence of osteoporosis within the aging society is becoming a major public
health problem. Such diseases have a negative impact on Quality of Life and an
urgent issue to find prevention and treatment methods. Currently, correlation
between the microstructural parameters and the mechanical properties is shown by
using an X-ray microtomography. In this study, the influence of the cancellous
bone region on the correlation between the microstructural parameters, calculated
by using X-ray microtomography images, and Young’s modulus, which were
obtained from the compression test, was clarified by targeting cancellous
bone specimens of various regions, obtained from bovine femur. Cancellous bone
specimens were obtained from the right femur of a bovine for the compression
test. The correlation coefficient between Young‘s modulus and microstructural
parameters was calculated. Cubic specimen in 5mm had the highest correlation
coefficient between Young‘s modulus and microstructural parameters.
Additionally, when specimen regions were 4 or 5mm, the standard deviation of
each microstructural parameter had the smallest value, except for Trabecular
Separation and Mean Intercept Length 3. The cancellous bone region of the cubic
specimen in 5mm had a high correlation between microstructural parameters and
Young‘s modulus and the value of the microstructural parameters of the small
variation.
Keywords: cancellous bone, X-ray μCT, microstructural parameters,
compression test, specimen region.
Keywords
cancellous bone, X-ray μCT, microstructural parameters,
compression test, specimen region.
Related Book
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