Particle Motion In Coronary Serial Stenoses
Author(s)
S. I. Bernad, A. Totorean, E. S. Bernad & R. Susan-Resiga
Abstract
Atherosclerosis creating a constriction can significantly alter the local blood flow
dynamics. From a biological aspect, the changes that take place in the flow have
a profound effect on the structure and function of the arterial wall and the
development of the disease. The purpose of this paper was to non-invasively
assess hemodynamic parameters such as wall shear stress, wall pressure and
particle depositions with computational fluid dynamics (CFD) in coronary artery
serial stenoses. A 3-D model of a serial stenosed RCA was reconstructed based
on multislice computerized tomography images. Energy loss associated with
such flow expansion after each constriction will be large and consequently the
pressure drop will be higher. Pressure drop across the stenoses ST1 and ST3 is
lower (4.62 mmHg and 4.81 mmHg respectively) during the time T2 = 0.79s, but
is significant during the peak systole T1 = 0.26s. The maximum WSS in the
proximal stenosis ST1 is about 254 Pa, and in the distal stenosis ST3 are 232 Pa.
One diameter downstream of the each stenosis, the WSS is low because of the
formation of the recirculation zone.
Keywords: blood flow, coronary artery diseases, hemodynamics, pressure drop,
wall shear stress.
Keywords
Keywords: blood flow, coronary artery diseases, hemodynamics, pressure drop,
wall shear stress.
Related Book
Other papers in this volume
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