The Relation Between Stroke Work And
End-diastolic Volume In The Ventricles
Author(s)
R. M. Shoucri
Abstract
Several experimental studies have been published in the literature about the
apparent linearity of the relation between stroke work (SW) and end-diastolic
volume (Ved), which is usually referred to as the preload recruitable stroke work
(PRSW). Experimental results seem to suggest that in the study of the
performance of the ventricles the PRSW relation gives more consistent results
compared to the variability of the parameters based on the end-systolic pressurevolume
relation (ESPVR). In this theoretical study it is shown that the relation
between SW and Ved is non-linear. Moreover it is shown that this relation can be
described by the same parameters used to describe the ESPVR. Applications to
experimental data published in the literature are discussed.
Keywords: preload recruitable stroke work, end-systolic pressure-volume
relation, preload of left/right ventricular ejection, pressure-volume relation in
the ventricles, active force of the myocardium, peak isovolumic pressure.
1 Introduction
The relation between stroke work (SW) and end-diastolic volume (Ved) is also
called the preload recruitable stroke work (PRSW) (Glower et al [1], Little and
Cheng [2]). The PRSW relation shows an apparent linearity and is considered as
a way to express the Frank-Starling mechanism; the larger the initial stretch of
the cardiac muscle, the stronger is the contraction of the myocardium. It can be
used to describe the contractility of the cardiac muscle and appears to give more
consistent results than the parameters derived from the end-systolic pressurevolume
relation (ESPVR) (Suzuki et al [3], Karunanithi et al [4]).
Keywords
preload recruitable stroke work, end-systolic pressure-volume
relation, preload of left/right ventricular ejection, pressure-volume relation in
the ventricles, active force of the myocardium, peak isovolumic pressure.
Related Book
Other papers in this volume
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