Dental Pulp Responses To Biphasic Calcium
Phosphate Cement Containing Buffer Solution
In The Liquid Phase
Author(s)
M. Yoshikawa & T. Toda
Abstract
We developed a novel biphasic calcium phosphate cement of dibasic calcium
phosphate dihydrate and tetracalcium phosphate as a root canal filling material.
For endodontic clinical use, the physical properties and tissue responses were
estimated. The pH level ranged from 8.2 to 8.6. Low crystalline hydroxyapatite
was recognized by XRD analysis. Mutually connected platy particles and
spherical particles were observed by SEM examination. The particles were
separated from each other by about 10 µm. Dental pulp responses to the cement
was estimated in mandibular first molar in vivo. Hard tissue was formed in the
middle of root canal by placement of the cement on the amputated pulp at the
orifice. When the cement was placed on the pulp amputated at the middle in the
root canal, cementum-like hard tissue was formed at the apex. Pulp amputation
and placement of the cement at the apical portion, mild inflammatory responses
to the cement were found in the periapical area. The cement in the alveolar bone
defect via the root canal promoted the reconstruction of periapical alveolar bone
defect. It is concluded that the cement is suitable for endodontic bioactive
material because of hard tissue inductiveness.
Keywords: calcium phosphate cement, dental pulp, hard tissue formation.
1 Introduction
It is known that dental pulp tissue (pulp) is surrounded by hard tissue of dentine.
Moreover the dentine of the coronal portion is covered with enamel, and dentine
of the tooth root is covered with cementum. Hard tissue defect caused by injury
or dental caries is restored with resin or metals. Pulp is often exposed in the oral
environment due to tooth fracture or dental caries. Pulp is immature, and shows
Keywords
calcium phosphate cement, dental pulp, hard tissue formation.
Related Book
Other papers in this volume
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