Pharmaceuticals And Personal Care Product
Residues In The Environment:
Identification And Remediation
Author(s)
E. Heath, T. Kosjek, P. Cuderman & B. Kompare
Abstract
In this paper we investigate the possible impact on the ecosystems of the active
ingredients in pharmaceutical and personal care products (PPCPs). These
molecules are in their nature biologically active substances whose effects, once
released into the environment, remain unclear. Commonly used drugs and
cosmetics have been detected in drinking and surface waters suggesting possible
consequences for environment and human health. Considering the possible
bioaccumulation in the food chain and chronic toxicity due to a combination
effect it is necessary to better understand their environmental fate.
Pharmacologically and cosmetic active substances involved in our study were
chosen according to their wide application in central Europe and to their
suspected toxicity and bioaccumulation (nonsteroidal anti-inflammatory drugs -
NSAIDs, sunscreen agents, antiseptics). For isolation and identification of the
selected compounds GC-MS procedure has been developed in our laboratory. To
determine the presence of PPCP in the Slovene aquatic environment, different
water samples (river, potable, well, lake, sea, swimming pool and waste water)
were analyzed. The results show that the average PPCP contamination in
Slovenian waters is comparable to published results for Central and Western
Europe. To understand the environmental fate of these substances we studied the
biodegradation paths in controlled conditions using laboratory scale bioreactor
facilities. Degradation experiments were made with spiked water samples of
different concentrations of pollutants (1µg/L-1ng/L) starting with activated
biomass from the active wastewater treatment plant. After 6 months of
continuous operation, a steady removal of all observed compounds (NSAID
representatives) was achieved (up to 90%). In the future other PPCP
representatives will be studied and the reactor configuration will be optimized.
Keywords: pharmaceutical, personal care products, NSAIDs, UV filters,
antimicrobial, analytical procedure, environmental samples.
Keywords
pharmaceutical, personal care products, NSAIDs, UV filters,
antimicrobial, analytical procedure, environmental samples.
Related Book
Other papers in this volume
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