The Variation Of Dobutamine Induced
Heart Stress With Heart Rate
Author(s)
A. K. Macpherson, S. Neti, C. Chutakositkanon, M. Averbach
& P. A. Macpherson
Abstract
Dobutamine stress echocardiography is a common test to provoke myocardial
ischemia in patients unable to undergo routine exercise stress testing. Heart rate
elevation, achieved by staged increases in dobutamine doses, acts as a surrogate
for exercise. The physicians monitor the ECG of the patient and
echocardiographic images to evaluate for myocardial ischemia. However, the
actual mechanical stress on the heart is not readily available to the physician. The
motivation for the present preliminary study is to both investigate the feasibility
of producing such information for clinicians as well as to investigate the
variation between different patients as the heart rate varies. Echocardiograms
were obtained from three patients undergoing dobutamine stress tests. Using
standard equations of motion, the surface shear stress at the surface of the left
ventricle was calculated. The average shear stress around the left ventricle is
shown, as well as the peak stresses at selected locations as a function of time. It
was found that generally the surface shear stress increased with heart rate around
most of the left ventricle. While the time averaged shear stress may be important
for diagnosis, the maximum shear stress is probably the limiting factor in
terminating testing.
Keywords: heart stress, dobutamine testing, heart rate, heart diagnosis.
Keywords
heart stress, dobutamine testing, heart rate, heart diagnosis.
Related Book
Other papers in this volume
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