Microvascular Disorders Induced By
Malaria Infected Red Blood Cells:
A Computational Mechanical Study Using
The Biological Particle Method
Author(s)
T. Yamaguchi, H. Kondo, Y. Imai & T. Ishikawa
Abstract
We simulated malarial microvascular blood flow disturbances by using a new
particle method of biological solid-fluid interaction analysis especially
developed for the analysis of malaria infection. Particle based spatial
discretization and the sub time step time integration could provide us with stable
computations for micro scale blood flow involving interaction with many cells.
We performed numerical simulation of the stretching of infected red blood cells
and the results agreed well with experimental results. Our model successfully
simulated the flow of infected red blood cells into narrow channels.
Keywords: malaria, computational fluid dynamics, particle method, red blood
cell, microcirculation, mechanical properties of cell membrane.
Keywords
malaria, computational fluid dynamics, particle method, red blood
cell, microcirculation, mechanical properties of cell membrane.
Related Book
Other papers in this volume
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