A Mathematical Model To Predict The
Performance Of Advanced Therapies In
Wound Healing
Author(s)
J. Ko, S. Dickman & V. W. Li
Abstract
Wound healing is a complex, dynamic process. The ability to simulate this process
using mathematical models that incorporate quantitative data on growth factors,
tissue repair cells and matrix components would be a powerful tool to predict,
analyze, and optimize new therapies. We present such a mathematical framework
based on a system of ordinary differential equations and wound healing parameter
values fromthe established literature. In contrast to conventional therapy, advanced
modalities can augment certain components of the healing process in a measurable
fashion. The performance of specific wound therapies can be simulated and compared
to other therapies.We have enhanced the model by incorporating parameters
of clinical practice used in the real world setting. This approach has application to
predictive performance analysis and optimization of new advanced modalities and
determination of best clinical practice.
Keywords: wound healing, differential equations, bifurcation.
Keywords
wound healing, differential equations, bifurcation.
Related Book
Other papers in this volume
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